Via The 9, here’s Not Starring, a database of films and the actors who weren’t cast in them:
Notstarring.com is a movie trivia database focusing exclusively on movie stars and the roles they turned down, auditioned for, got fired from, or simply didn’t get. All trivia is submitted by users, so please help us build the archive today!
Famously, Tom Selleck turned down Indiana Jones because he was committed to some goofy TV series. Notably, Winona Ryder has eleven misses to her name.
Incidentally, The 9 is a blatant ripoff of Rocketboom. Let’s see–attractive woman talks to camera and reviews Internet memes and kooky videos–where have I seen that before? Of course, it’s considerably more professional and less quirky, which makes it all the less compelling. Tim thinks it’s the end of civilization as we know it.
DarrenBarefoot.com 
All I know is it seemed to be the end of Safari every time I loaded their web page.